Uro-oncology deals with the cancers of the genito-urinary system in males and urinary system in females. It is a well-established sub-specialty of Urology. The management of urological cancers is changing rapidly. Majority of the patients requires multimodality treatment comprising Urologists, Radiation Oncologists, Medical Oncologists, Reconstructive Surgeons, Uropathologists, Radiologists, Nuclear Physicians, Social Workers, Clinical Psychologists, Physiatrists, Pain & Palliative Care Physicians, etc. for the best outcome. It is the need of the day to have a devoted comprehensive programme for Urological Malignancies (Cancers) considering the new advancements in treating the cancers of genito-urinary system.